Jobs at TopChem
We are always looking for new talent to join our team. We offer competitive terms and conditions of employment as well as a challenging multi-project environment where you can develop your career in the Pharmaceutical industry. We have been growing steadily since we established in 2007 and offer great opportunities for career development within the Company.
- Our main operations are based in Ballymote County Sligo where all new product development, manufacturing, QA and QC take place.
The Company currently manufactures a range of commercial products and has a strong pipeline of new products entering development.
Contact Us to find out more about careers at TopChem.
Development Manager
We now require a Development Manager to join our Management Team. The Development Manager will lead our new product development and technical services team. You will play a key role in managing the development, optimization and scale-up of our new products.
Essential Duties and Responsibilities
Reporting to the Managing Director, the Development Manager will work closely with our QC, and Production teams in developing safe, cost effective, reliable manufacturing processes delivering high quality products. This is a key management role which demands a blend of excellent technical, project management and people skills to deliver new product projects.
Education and Experience
To be considered for this role you must have a PhD in chemistry with significant experience in organic synthesis and a minimum of five years experience working in the development of active pharmaceutical ingredients in a cGMP environment. This is an excellent opportunity to lead a young team in an expanding and dynamic independent Irish pharmaceutical company with ambitions for strong growth.
Applications to Dr Donal Coveney, Managing Director, TopChem Pharmaceuticals Limited, Ballymote Business Park, Ballymote, Co. Sligo or .
Development Chemist
We now require a Development Chemist to join our product development team. You will play a key role in developing and optimizing synthetic chemical and purification processes for our new product pipeline.
Essential Duties and Responsibilities
The Development Chemist will work closely with our QC, and Production functions in developing safe, cost effective, reliable manufacturing processes delivering high quality products. This is a role which involves mainly laboratory work, both synthetic and analytical.
Education and Experience
To be considered for this role you must have an MSc or PhD in chemistry with significant experience in organic synthesis. This is an excellent opportunity to join a young team in an expanding and dynamic independent Irish pharmaceutical company.
Applications to Dr Donal Coveney, Managing Director, TopChem Pharmaceuticals Limited, Ballymote Business Park, Ballymote, Co. Sligo or .
News
- November 2021: TopChem has been audited remotely by US FDA and we are delighted to advise that we have successfully passed this latest inspection.
- September 2021: TopChem ships the first quantities of Zinc Sulfate suitable for use in injectable drug product formulations.
- July 2021: We are pleased to confirm that we have completed the installation of our fifth manufacturing suite and have commenced manufacturing a new product in this suite. This demonstrates our ongoing commitment to expand our business and to offer our customers new products and technologies.
- February 2021: TopChem has successfully passed our fourth EU cGMP audit, performed by the HPRA.
- January 2021: Our recent US Patent 10836705 details our proprietary process for the manufacture of very high purity Bretylium Tosylate. TopChem is the only US approved manufacturer of this API. Bretylium Tosylate Injection is indicated in the prophylaxis and therapy of ventricular fibrillation. Bretylium Tosylate Injection is also indicated in the treatment of life-threatening ventricular arrhythmias, such as ventricular tachycardia that have failed to respond to a first-line antiarrhythmic agent, such as lidocaine. This product had been off the market for many years due to the lack of availability of the API. Dr John Somberg, an eminent US cardiologist has been instrumental in bringing this life-saving medicine back to the US market. TopChem collaborated with Dr Somberg and the drug product manufacturing partner, Pharmaceutics International Inc. to secure the US approval and relaunch of Bretylium Tosylate in the US market.
- October 2020: A second shipment of Covid-19 test reagent was supplied to Sligo University Hospital to support the testing laboratory at our local hospital.
- April 2020: We are delighted to have supplied the first lot of Covid-19 test reagent (guanidinium thiocyanate lysis buffer) to Sligo University Hospital. TopChem produced this reagent at cost and we are very pleased to be able support the national effort in our small way in these difficult times.