Jobs at TopChem

We are always looking for new talent to join our team. We offer competitive terms and conditions of employment as well as a challenging multi-project environment where you can develop your career in the Pharmaceutical industry. We have been growing steadily since we established in 2007 and offer great opportunities for career development within the Company.

  • Our main operations are based in Ballymote County Sligo where all new product development, manufacturing, QA and QC take place.

The Company currently manufactures a range of commercial products and has a strong pipeline of new products entering development.

Contact Us to find out more about careers at TopChem.

Development Chemist

We now require a Development Chemist to join our product development team. You will play a key role in developing and optimizing synthetic chemical and purification processes for our new product pipeline.

Essential Duties and Responsibilities

The Development Chemist will work closely with our QC, and Production functions in developing safe, cost effective, reliable manufacturing processes delivering high quality products. This is a role which involves mainly laboratory work, both synthetic and analytical.

Education and Experience

To be considered for this role you must have an MSc or PhD in chemistry with significant experience in organic synthesis. This is an excellent opportunity to join a young team in an expanding and dynamic independent Irish pharmaceutical company.

Applications to Dr Donal Coveney, Managing Director, TopChem Pharmaceuticals Limited, Ballymote Business Park, Ballymote, Co. Sligo or .


  • January 2021: Our recent US Patent 10836705 details our proprietary process for the manufacture of very high purity Bretylium Tosylate. TopChem is the only US approved manufacturer of this API. Bretylium Tosylate Injection is indicated in the prophylaxis and therapy of ventricular fibrillation. Bretylium Tosylate Injection is also indicated in the treatment of life-threatening ventricular arrhythmias, such as ventricular tachycardia that have failed to respond to a first-line antiarrhythmic agent, such as lidocaine. This product had been off the market for many years due to the lack of availability of the API. Dr John Somberg, an eminent US cardiologist has been instrumental in bringing this life-saving medicine back to the US market. TopChem collaborated with Dr Somberg and the drug product manufacturing partner, Pharmaceutics International Inc. to secure the US approval and relaunch of Bretylium Tosylate in the US market.
  • October 2020: A second shipment of Covid-19 test reagent was supplied to Sligo University Hospital to support the testing laboratory at our local hospital.
  • April 2020: We are delighted to have supplied the first lot of Covid-19 test reagent (guanidinium thiocyanate lysis buffer) to Sligo University Hospital. TopChem produced this reagent at cost and we are very pleased to be able support the national effort in our small way in these difficult times.
  • October 2019: Adenine. Our latest new product has shipped to an international customer.
  • October 2019: We are pleased to announce the commencement of the expansion of our R&D laboratories to strengthen our research capabilities and to support our growing global business.
  • February 2019: Bretylium Tosylate ANDA Approved in the US. We are delighted with the recent news of the approval of the Bretylium Tosylate ANDA #204386 sponsored by our partner Academic Pharmaceuticals Inc. The drug product will be manufactured by PII. TopChem Pharmaceuticals Ltd is the exclusive supplier of the Active Ingredient and we look forward to working with our partners to bring this life-saving medicine back to the US market. Dr John Somberg, CEO of Academic stated that "TopChem was instrumental in making this critical active ingredient available to the exceptionally high quality standards required".

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